Delay the fourth vaccine; Immediately the fourth dose (or second booster) may be given to immunocompromised adults.
The European Center for Disease Control and the European Medicines Agency's Kovid-19 Task Force found that the use of the fourth dose of the MRNA Covid-19 vaccine in the general population was too early. However, both agencies have agreed to give a fourth dose (or a second booster) to adults aged 80 and over, and the dose will be decided after reviewing data on the high risk of severe covid-19 in this age group and the protection provided by the fourth dose.
Data indicate that the second booster provides additional protection against serious diseases, although the duration of vaccine benefits is not yet known, and evidence is still limited.
The agencies say the evidence for the effects of the fourth dose comes mainly from Israel. Data indicate that the second booster, which is given at least four months after the first booster, restores antibody levels without raising any new safety concerns.
The European Center for Disease Control and the European Medicines Agency said there was currently no clear evidence in the European Union that vaccine protection against the serious disease is significantly reduced in adults with normal immune systems between the ages of 60 and 79, so there is no clear evidence for immediate use of the fourth dose.
However, a fourth dose of Covid vaccine is recommended for people over 65 years of age. The National Immunization Advisory Committee (NIAC) has recommended a fourth dose of the Covid vaccine for all people 65 years of age and older.
It also recommends that children 12 years of age and younger who are immunocompromised and children 5 to 11 years of age who are immunocompromised complete an extended primary course, i.e. three doses of the vaccine in total.
Health Minister Stephen Donnelly said he had taken the advice of the NIAC and plans to launch this vaccine dose had already begun at HSE. He said the NIAC had advised a period of six months between the new dose and the previous dose, but in some cases an interval of four months would be appropriate.
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